Blood Chemical ‘Fingerprint’ Analysis May Help Diagnose Fibromyalgia

Blood Chemical ‘Fingerprint’ Analysis May Help Diagnose Fibromyalgia
Detailed profiling of the biological content of blood samples can help diagnose fibromyalgia (FM) and differentiate it from other diseases such as rheumatoid arthritis or lupus, a study suggests. The new analysis method was described by a team led by researchers from Ohio State University and uses the energy vibrational pattern of each biological molecule to identify FM-specific biomarkers. “Advantages of such a methodology, if developed and honed to reproducibility, would be a capability for identifying specific treatment subsets for FM as well as identifying new targets as differentiated from each other metabolically,” researchers stated. This experimental blood test was described in the study “Metabolic fingerprinting for diagnosis of fibromyalgia and other rheumatologic disorders,” published in the Journal of Biological Chemistry. FM is a complex disorder mainly characterized by chronic widespread pain. However, most patients often report other symptoms such as fatigue, sleep problems, cognitive impairments, and affective symptoms, which can overlap with other medical conditions. The underlying mechanisms involved in FM development are still poorly understood, but studies have demonstrated that environmental and clinical factors may contribute. This makes FM diagnosis a challenge for physicians. Vibrational spectroscopy technology is being developed for rout
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