Urinalysis Can Detect Gut Microbiome Imbalance Linked to Fibromyalgia, Study Suggests

Urinalysis Can Detect Gut Microbiome Imbalance Linked to Fibromyalgia, Study Suggests
Changes in gut metabolism can contribute to how the brain processes generalized pain signals in people with fibromyalgia. These changes were detected through urinalysis, which may represent a new non-invasive strategy to diagnose and monitor these patients. The study, “The GC-MS metabolomics signature in patients with fibromyalgia syndrome directs to dysbiosis as an aspect contributing factor of FMS pathophysiology,” was published in Metabolomics. The gastrointestinal tract houses a complex and dynamic population of bacteria and other microorganisms, commonly called gut microbiome, which exert a marked influence on a person's health and disease onset. Analysis of small molecules derived from normal metabolism — known as metabolites — within cells, biofluids, or tissues holds promise for the identification of potential diagnostic biomarkers for several human diseases. Metabolic imbalance has been shown to influence fibromyalgia, and studies have linked chronic pain syndrome to bacterial overgrowth within the small intestine. Fibromyalgia was also associated with changes in energy metabolism and gut metabolome — the total number of metabolites present within the gut. Based on this, a team led by researchers from the
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