Leptin Tied to Bodily Pain, Predicts Fibromyalgia Pain Levels, Researchers Say

Leptin Tied to Bodily Pain, Predicts Fibromyalgia Pain Levels, Researchers Say
Leptin – a factor well-known for its role in controlling appetite – might be a driver of bodily pain, according to a new report. Investigating levels of the molecule in both women with fibromyalgia and healthy women has provided scientists with clues of the underlying processes of pain signaling and might lead to better future pain treatments. Last week, Fibromyalgia News Today reported on the scientific progress of a research team from the University of Alabama at Birmingham, investigating brain-immune interactions in fibromyalgia patients. The study described the team's efforts to understand leptin’s role in pain signaling. Earlier research has shown that the appetite-controlling molecule is also regulated by sleep and infection, and has been linked to inflammatory diseases such as rheumatoid arthritis, lupus, and multiple sclerosis. The report, titled "Association of Leptin with Body Pain in Women," is actually composed of two studies. The first small pilot study followed three women over 25 days who were affected by fibromyalgia, analyzing both leptin and pain on a daily basis. The findings, published in the Journal of Women's Health, show that leptin levels fluctuated along with reported pain, with higher levels on days when women experienced more pain. The second study explored previously collected data from the Women’s He
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