Study Shows Melatonin Associated With Fibromyalgia Pain Improvement

Study Shows Melatonin Associated With Fibromyalgia Pain Improvement
A recent study entitled "Melatonin analgesia is associated with improvement of the descending endogenous pain-modulating system in fibromyalgia: a phase II, randomized, double-dummy, controlled trial", published in the BMC Pharmacology and Toxicology journal, observed that melatonin alone or in combination with amitriptyline significantly reduced pain in fibromyalgia patients. Fibromyalgia is a disease characterized by widespread pain lasting for months to years (usually throughout the life of an affected patient) and a painful response to pressure in various specific body areas. Furthermore patients often also have stiffness of the body, fatigue, sleep disturbances, anxiety and depression. It estimated to affect as much as 2 to 8% of the population with 7 to 9 times more women affected compared to men. Sleep disorders and alteration of the circadian rhythm (the physiological oscillation of body metabolism through the 24 hours) are very common in fibromyalgia patients. Melatonin is one of the main hormones in the body responsible for circadian rhythm synchronization. There is some evidence that melatonin treatment improves different types of chronic long-lasting pain, namely inflammatory and neuropathic pain. Related: Read more about the latest chronic pain and pain management news. As the available evidence on melatonin treatment efficacy for fibromy
Subscribe or to access all post and page content.