Hormonal Changes May Affect Fibromyalgia Onset

Hormonal Changes May Affect Fibromyalgia Onset
The disparity between men and women in developing fibromyalgia, where the female to male ratio is 7:1, causes many researchers to be suspicious of a link between sex hormones and chronic pain. Hormones may have a critical role in the onset, maintenance, and inhibition of pain. To determine if the clinical features and timing of hormonal changes have a relationship in a cohort of ethnically diverse individuals, a group of researchers from University of Miami Miller School of Medicine conducted a retrospective chart review of patients at the academic medical center in a period of one year. "This retrospective chart review investigated differences in the prevalence of medical comorbidity between women with fibromyalgia and a control group women with chronic pain without fibromyalgia," wrote Dr. Larry Brooks to describe the team's article, "Assessing the Prevalence of Autoimmune, Endocrine, Gynecologic, and Psychiatric Comorbidities in an Ethnically Diverse Cohort of Female Fibromyalgia Patients: Does the Time from Hysterectomy Provide a Clue?", which was published in Journal of Pain Research. "The specific aims were to compare the prevalence of autoimmune, psychiatric, endocrine, gynecologic pathology, the relationship between timing of gynecologic surgery, and pain onset." When reviewing patient charts, Dr. Brooks and three medical residents gathered data concerning diagnosis, year of pain onset, medical comorbidities, psychiatric comorb
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