Tramadol/Acetaminophen Improves Quality of Life in Chronic Pain Patients

Tramadol/Acetaminophen Improves Quality of Life in Chronic Pain Patients
Fibromyalgia patients who were given analgesic in a randomized, double-blind study experienced a reduction in pain and an improvement in health-related quality of life. Before the study, patients experiencing pain had significant impairment of their health-related quality of life, but during the study, the patients' pain relief directly correlated to an increase in health-related quality of life. Researchers at Oregon Health and Science University in Portland and collaborators and other institutions were supported by Ortho-McNeil Pharmaceutical, Inc., to conduct the study. The study, entitled, "Impact of Fibromyalgia Pain on Health-Related Quality of Life Before and After Treatment With Tramadol/Acetaminophen," was published in the journal Arthritis & Rheumatism. A total of 313 fibromyalgia patients with moderate-to-severe pain were recruited for the study. Patients received tramadol/acetaminophen four times a day, every day, for up to a possible allotment of 91 days. The ratio of tramadol to acetaminophen was 1-to-8. The two medications were selected to be given together because tramadol and acetaminophen work through different mechanisms to achieve the goal of pain relief. At baseline, patients were evaluated for pain using the visual analog scale (VAS), where no pain is a score of 0 and extreme pain is a score of 100 mm. Patients were grouped into four categories based on pain score and evaluated for differences in outcome measures from the beginni
Subscribe or to access all post and page content.

Leave a Comment

Your email address will not be published. Required fields are marked *