Fibromyalgia and Neuropathic Pain Have Both Differences and Similarities in Sensory Profiles

Fibromyalgia and Neuropathic Pain Have Both Differences and Similarities in Sensory Profiles
FMRalf Baron from the Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein in Germany and colleagues, compared co-morbities and sensory perceptions in patients with Painful Diabetic Neuropathy and Fibromyalgia. The study entitled “Fibromyalgia and neuropathic pain - differences and similarities. A comparison of 3057 patients with diabetic painful neuropathy and fibromyalgia,” was recently published in the journal BMC Neurology. Painful diabetic neuropathy (DPN) is a chronic neuropathic pain syndrome caused by a metabolic damage of primary afferent neurons. The sensory symptoms include numbness, prickling, burning or electric shocks. Fibromyalgia (FM) is a chronic pain condition characterized by widespread pain mainly perceived in deep somatic tissues, i.e., in muscles and joints. Moreover, the patients have abnormal pain sensitivity and frequent additional comorbidities like sleep disturbances and affective disorders. Patients with diabetic neuropathy (DPN) and fibromyalgia (FM) differ substantially in pathogenetic factors and the spatial distribution of the perceived pain. However, similar abnormal sensory complaints and pain exists in both conditions. In this regard, the team of researchers conducted a multicenter trial in 450 outpatient centers, involving 1434 fibromyalgia pa
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