Fibromyalgia Experiments Reveals Positive Therapeutic Benefits of O. Basilicum Leaves’ Essential Oil

Fibromyalgia Experiments Reveals Positive Therapeutic Benefits of O. Basilicum Leaves’ Essential Oil
A new study revealed the potential analgesic effects of essential oils of O. basilicum leaves on chronic, non-inflammatory fibromyalgia pain.  This study entitled “Cyclodextrin-Complexed Ocimum basilicum Leaves Essential Oil Increases Fos Protein Expression in the Central Nervous System and Produce an Antihyperalgesic Effect in Animal Models for Fibromyalgia” was published in International Journal of Molecular Sciences by Simone S. Nascimento and Adriano A. S. Araújo, co-first authors of the study, and led by Dr. Lucindo J. Quintans-Júnior from the Laboratory of Pre-Clinical Pharmacology (LAPEC) at the Federal University of Sergipe in Brazil. Fibromyalgia is a chronic disorder of the locomotor system, affecting muscular and skeletal systems with unknown causes. This disease is characterized by chronic general pain, presence of tender points on physical examination, and symptoms such as tiredness, morning stiffness, sleep disorders and depression. The standard treatment for fibromyalgia consists mainly of antidepressants, calcium-channel modulators, muscle relaxants and analgesics. However, the prolonged use of these pharmacological compounds induce adverse events and many patients do not respond adequately to these therapies. Therefore, there is an urgent need to discover alternative therapies to overcome the limitations of the current treatments for chronic pain in fibromyalgia. The screening of natural compounds from medicinal plants or their derived metabolites has been a very useful strategy to discover potential new therapies for several diseases.  Essential oils extracted from several aromatic plants from countries like Brazil have been tested due to their unique biological properties. The Ocimum species (Lamiaceae) have been used to treat ce
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