Prolonged intervals of being inactive likely worsen symptoms of the disease in women with fibromyalgia (FM), regardless of their overall physical fitness, a recent study suggests. FM patients should be advised of that possibility by healthcare providers, the researchers recommend. The study,"Sedentary Time Accumulated in Bouts is Positively Associated with Disease Severity in Fibromyalgia: The Al-Ándalus Project," was published in the Journal of Clinical Medicine. Sedentary behavior, defined as sitting or reclining during waking hours with little energy expenditure, is a recognized risk factor for many conditions, such as cardiovascular disease and diabetes. Because sedentary behavior may be associated with disease outcomes regardless of one's physical activity levels, current physical activity guidelines recommend reducing sedentary periods. Previous findings highlight that both total and pattern of accumulation of sedentary time (ST) also are important.