According to prevention.com, there are 20 million people worldwide who suffer from fibromyalgia and many more who may be experiencing symptoms but have not yet been diagnosed. Here are 11 of the most common symptoms associated with fibromyalgia: The number one symptom is global pain. Fibromyalgia is a disorder which affects the central nervous system and this manifests as acute pain, mainly in the arms, legs and torso but the pain can be felt over the entire body and deep into the muscles and joints. A study finds that Lyrica reduces pain in conditions such as fibromyalgia. Find out more.