Study Shows Fibromyalgia Patients Find Combination Therapy a More Effective Pain Treatment

Study Shows Fibromyalgia Patients Find Combination Therapy a More Effective Pain Treatment
Canada's Queen's University scientist Ian Gilron has found a more effective way to treat fibromyalgia by combining Lyrica (pregabalin), an anticonvulsant drug, with Cymbalta (duloxetine), an antidepressant. The study, “Combination of pregabalin with duloxetine for fibromyalgia: a randomized controlled trial,” was published in the journal Pain. The results demonstrated that the combination of the two drugs can safely improve outcomes in fibromyalgia, includ
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  1. Bonnie Watson says:

    I started with Gabapentin only then after several months Cymbalta was added. Not seeing much relief and it’s been quite awhile. Is Lryica in the same field as Gabapentin? I have appt. w/reg. Dr. and rhumetologist this month and would like to talk to them about this study. I don’t believe either of them (or for that matter most Dr.s) follow the studies that I see. TIA for any input on your results.

  2. Kelly says:

    I have been on both Cymbalta & Lyrica, as well as Tridural (Tramadol) and none of the helped. I have also had nerve block therapy, that is, analgesics injected directly into the nerve. The Medical Marijuana therapy I am now undergoing has given me the best results and most relief, out of all other medications I have taken for my Fibro over the past 19+years

    • Erma says:

      I also have started on medical marijuana and is the only thing that gives me energy and takes a lot of my pain. My sister who doesn’t have fibromyalgia told me… “Well, that’s what you say” well it does… And I pray that she will never experience the pain I feel.

  3. julie spear says:

    I currently take gabapentin 2 3xdaily but all they seem to do is relax me & make me sleepy, I was diagnosed with fibromyalgia in march, I also take sertraline for depression/anxiety which I’ve been taking for 3yrs but don’t think they work now! I take one antihistamine daily all year round for allergy’s am allergic to all types of fur/feathers animals in gen & pollen. I take omeprazole if I have to take ibuprofen for extra pain relief & take paracetamol on a daily basis wouldn’t be without them. After a burst of energy yesterday I’m really tired today. I’m lucky if I have 2-3 days out of a week when I am active. I also have gained even more weight & swear that’s down to the gabapentin? Help I need answers to what the best step forward is to take, without my Dr fobbing me off with other meds that may or may not work?

  4. Michelle says:

    Lyrica and Cymbalta both cause weight gain, this doesn’t help with the pain the extra weight causes. They also both effective your sexual drive. So if you already have depression anxiety the weight gain and loss of desire to be with your partner or spouse will definitely make them worse. The side effects outweigh the minimal pain reduction. Neither take the pain away completely unless you are fortunate to have a physician who also prescribes a good pain medication.

  5. Denise says:

    My husband had been on Cymbalta for a year with terrible morning sickness lasting half a day. His rheumatologist then added Gabapentin along with the Cymbalta and he has felt the best he has in two years for the past few months. He also uses medical marijuana for pain. He is underweight, so any weight gain is appreciated. He is up a few pounds but must watch that he eats enough so that he doesn’t go back down. He finally feels like getting back to working out a bit like he used to. He was quite athletic prior to diagnosis of a fibromyalgia-type condition that could never be confirmed with blood tests.

    • Geraldine VanRaalte says:

      Hi Denise. I came across your comment and it struck a chord with me because my 42 yr old husband is also on Cymbalta for fibro (as well as medical marijuana). He also feels terrible after taking the Cymbalta, but the benefits have outweighed that so far. Today, the rheumatologist suggested that we add Gabapentin. He said it will help with the ongoing sleep issues.
      Could you comment on how your husband is doing now? Is he still on those 3 meds, and are they still helping? I’m so hesitant to add more to the mix, so your input is appreciated.

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