Lower Serotonin Levels Associated with More Severe Fibromyalgia, Study Shows

Lower Serotonin Levels Associated with More Severe Fibromyalgia, Study Shows
Fibromyalgia patients with lower serotonin levels are more likely to have a severe form of the disease, while there is no apparent relationship between vitamin D levels and disease severity, researchers found. The study, "Clinical association of vitamin D and serotonin levels among patients with fibromyalgia syndrome," was published in the journal Neuropsychiatric Disease and Treatment. Fibromyalgia is the second most common rheumatic disorder. Common symptoms include chronic pain, mood changes, tiredness, and sleep disorders. The exact cause of fibromyalgia remains unknown, but studies have suggested that the dysregulation, or improper working, of specific proteins and small molecules are related to disease progression and severity. Vitamin D is essential for the function of muscles and bones, and its deficiency can lead to chronic pain. Studies have connected fibromyalgia to low levels of this vitamin. However, the direct relationship between Vitamin D and fibromyalgia is still unclear. Serotonin is a neurotransmitter — molecules that mediate the communicati
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