Soursop Leaf Extract Relieves Fibromyalgia Symptoms in Mice, Study Shows

Soursop Leaf Extract Relieves Fibromyalgia Symptoms in Mice, Study Shows
Supplementation with an extract of soursop leaves alleviated pain symptoms, depression, and anxiety in a mouse model of fibromyalgia, researchers report. Their study, “Diets supplemented with Annona muricata improve the symptoms of fibromyalgia,” was published in the journal PharmaNutrition. Fibromyalgia symptoms such as chronic muscular pain, depression, and anxiety can affect patients' health-related quality of life. The medicinal properties of soursop extract are well-reported in the literature, according to the study's authors. Its benefits in easing symptoms of inflammation, pain, diabetes, infections, and cancer have been validated in laboratory tests. However, its role in relieving fibromyalgia symptoms has not been very well-explored. Soursop is the common name of the Annona muricata L, a tree native to the central and South America, found especially in the Amazon region. Researchers supplemented the standard diet of mice with different concentrations of soursop leaf extract (15% and 30%) for four weeks, after which fibromyalgia was experimentally induced in the mice to test the effectiveness of the extract in preventing fibromyalgia symptoms. Intermittent cold stress (ICS) was used to induce fibromyalgia-like symptoms. A total of 60 mice were included. They were divided into six groups that all received the standard diet with or without varying supplements. These six mouse groups included healthy controls, ICS controls, and four
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