Hyperreactive Brain Network May Be Cause of Chronic Pain in Fibromyalgia, Study Suggests

Hyperreactive Brain Network May Be Cause of Chronic Pain in Fibromyalgia, Study Suggests
A new study suggests a hyperreactive brain network may be the underlying cause of chronic pain in fibromyalgia. The report shows that brain networks of fibromyalgia patients have an underlying hypersensitivity that leads them to overreact to stimulation in an explosive, widespread, and synchronized manner. This type of response is called explosive synchronization (ES), a phenomena that occurs both in biological and physical networks, such as during seizures or power grid failures. The study, “Functional Brain Network Mechanism of Hypersensitivity in Chronic Pain,” was published in the journal Scientific Reports. "For the first time, this research shows that the hypersensitivity experienced by chronic pain patients may result from hypersensitive brain networks," Richard Harris, the study's co-senior author and associate professor of anesthesiology at the Chronic Pain and Fatigue Research Center at Michigan Medicine, said in a press release. The electrical activity of the brains of 10 female fibromyalgia patients were recorded by electroencephalogram (EEG), a noninvasive technique. EEG results revealed that fibromyalgia patients do indeed display brain network configurations with explosive synchronization properties. In each patient, researchers found a significant correlation between the degree of ES and the intensity of reported chronic pain. Researchers then used computer models of brain activity to s
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One comment

  1. Michaela says:

    This is really exciting news to read and wow, the description of being predisposed to an abrupt and explosive reaction to stimuli is exactly how I have been trying to describe how I feel for a long time.

    Here’s hoping, the research continues and provides more answers, clarity and recognition across the globe.

    If you are a young person with Fibromyalgia, I blog about my condition from time to time and I’d love to meet you. Please feel free to say hi anytime!!


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