Fibromyalgia Pain Symptoms Improve with Reduction of Blood Inflammatory Markers, Study Shows

Fibromyalgia Pain Symptoms Improve with Reduction of Blood Inflammatory Markers, Study Shows
Fibromyalgia (FM) patients treated with a low dose of Revia/Vivitrol (naltrexone) showed improved pain symptoms, a pilot study found. These patients also experienced significantly reduced inflammatory markers in their blood. The results, which addressed the use of Revia/Vivitrol in eight women with FM, were reported in a study titled, “Reduced Pro-Inflammatory Cytokines after Eight Weeks of Low-Dose Naltrexone for Fibromyalgia,” published in the journal Biomedicines. FM is not a classical inflammatory or immune-mediated condition, but the immune system is thought to be involved in the disease’s development. Revia/Vivitrol blocks opioid receptors and inhibits inflammation in patients with Crohn’s disease patients. The research team investigated the impact of this medication in blood inflammatory markers in FM patients. The team recruited women aged 18 to 65 (average age of 46) with a diagnosis of FM, according to the American College of Rheumatology 2010 diagnostic criteria. Researchers studied the women during two weeks before treatment to define a reference baseline. After this period, each participant self-administered a low dose of Revia/Vivitrol (4.5 mg), ta
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