Fibromyalgia Patients Stick with Combo Therapies Better Than Stand-alones, Study Reports

Fibromyalgia Patients Stick with Combo Therapies Better Than Stand-alones, Study Reports
Fibromyalgia patients stick with combination therapies better than stand-alone treatments, but the combo approaches are more expensive, according to a study that examined South Carolina health insurance claims. The results could reflect patients' belief that combination therapies do a better job, researchers said. They also said patients may stick with combos better because they reduce side effects. But to prove this, more studies are needed, they said. The study, "Healthcare Costs and Medication Adherence Among Patients with Fibromyalgia: Combination Medication vs. Duloxetine, Milnacipran, Venlafaxine, and Pregabalin Initiators," was published in the journal Pain Practice. Lyrica (pregabalin), Cymbalta (duloxetine), Savella (milnacipran), and Effexor (venlafaxine) were the four treatments that researchers from the University of Florida and the Medical University of South Carolina evaluated. Earlier studies suggested that combining Cymbalta, Savella, or Effexor with Lyrica generated better patients outcomes, but there was no real-world data on how patients stick with treatments. The research team looked at the records of 100 fibromyalgia patients on combination treatments, 655 patients on Lyrica alone, 713 on Cymbalta alone, 131 on Savella alone, and 272 on Effexor alone. Sixty-percent of the patients had muscle pain. Other fibromyalgia-related problems were nervousness, fatigue, abdominal pain, headache, and insomnia. Each affected less than 22 percent of the group, however. Depression, irrit
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