Scientists Find Link Between DNA and Chronic Widespread Joint Pain, a Fibromyalgia Symptom

Scientists Find Link Between DNA and Chronic Widespread Joint Pain, a Fibromyalgia Symptom
Scientists at King’s College London have discovered a link between specific alterations in DNA (called epigenetics) and chronic widespread joint pain, one of fibromyalgia’s main symptoms. Epigenetics corresponds to changes caused by modifications in gene expression rather than alterations on the genetic DNA code. Even though fibromyalgia is fairly common, its underlying causes are not fully understood and there are limited treatments available. There are no specific diagnostic tests for the condition and conventional screenings, like x-rays, are unable to detect the disease. Researchers believe their findings will help scientists worldwide develop a blood diagnostic test for fibromyalgia, which is estimated to affect one in every 25 people. The study reporting the findings was published in the journal PLOS ONE under the title “Are Epigenetic Factors Implicated in Chronic Widespread Pain?” The study was funded by Arthritis Research UK. “Fibromyalgia is influenced by genetic factors, but there are many complicated steps between gene and disease. Identifying measurable epigenetic links is a major step forward," Frances Williams, one of the authors of the study, said in a press release. "In addition, the results will inform future research in fibromyalgia as well as other chronic pain syndromes, such as irritable bowel syndrome.” The researchers used tw
Subscribe or to access all post and page content.


  1. Sha'ula says:

    Oh, be still my heart. Could this be the link we have been hoping would be found? I have only one sibling and he has fibro. as well. Coincidence? Probably not. I find this very encouraging, yet I have learned after 30 years not to get my hopes up until this type of research is repeated with a larger sample size and with the same outcomes.

    • Rebecca says:

      Yep. I’m tired of articles perpetuating the myth that Fibro can’t be diagnosed using tests. A handful of definitive tests do exist. However, only one is reimbursed by insurance. The news template describing Fibro needs to be corrected and updated already!

  2. Jay Thomas says:

    For those with military service exposures to Sarin or Organsphosphate Pesticides in Desert Storm, this may show the same DNA coding, but the treatment will vary.

  3. Kate says:

    This could be great news! My Son and daughter both have either CFS and Fibro j I myself have IBS with my fibro. People look at you and can’t see a physical injury so they tend to think you are just lazy or pretending. I work a full time job and a part time job so lazy is not in my vocabulary, but brain fog and pain are. I am so glad people are taking us seriously at last.

  4. I was diagnosed in 1999, in Feb.2017 I was hospitalized and they let me out only on threats from my husband and I. I was finally released 7 days after the fact. I am a smoker and of course unable to smoke in hospital. But after coming home I felt better than ever before. I figured it out the smoking was the culprit unable to contend , my body ws shutting down every time I smoked. So everyone said Shit, just quit smoking. It is now april 2018 and I am still fighting the battle. Please any advice is welcome.

Leave a Comment

Your email address will not be published. Required fields are marked *