Fibromyalgia Patients Should be Monitored for Hyperparathyroidism, Study Suggests

Fibromyalgia Patients Should be Monitored for Hyperparathyroidism, Study Suggests
Patients with fibromyalgia (FM) also may develop primary hyperparathyroidism (PHP), a disease that shares several symptoms with FM, according to a study by Brazilian researchers. The study, “High Frequency Of Asymptomatic Hyperparathyroidism In Patients With Fibromyalgia: Random Association Or Misdiagnosis?,” was published in the journal Revista Brasileira de Reumatologia. PHP is a disease characterized by a hyperactive parathyroid gland (high levels of parathyroid hormone - PTH) and consequent hypercalcemia (high levels of calcium in the blood). The condition affects mostly people older than 50 and post-menopausal women. The clinical diagnosis of PHP often is difficult because its symptoms are variable and similar to those of fibromyalgia, including musculoskeletal pain, cognitive disorders, insomnia, depression and anxiety. Most PHP patients have asymptomatic hypercalcemia, which is elevated levels of calcium without the presence of the classic manifestations of PHP. But another form of PHP also can occur, consisting of patients who have normal blood calcium levels and high levels of PTH in the absence of other known cause for this hormonal increase; that is called normocalcemic hyperparathyroidism. It has been proposed this would be the first phase of the disease, starting with elevated PTH only and then developing later into full PHP with high levels of calcium. “Despite the similarity between symptoms of FM and asymptomatic hyperparathyroidism, there are few publications evaluating this association,” the authors wrote. “This study aimed to determine the frequency of asymptom
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