Chemical Signature for Chronic Fatigue Syndrome Identified

Chemical Signature for Chronic Fatigue Syndrome Identified
Chronic fatigue syndrome (CFS) is a condition responsible for long-term pain and disability. It is separate from but often considered related to fibromyalgia. Unfortunately, CFS is a difficult to diagnose disease mainly because of its variable symptoms and the lack of a solid diagnostic laboratory test. But in a recent study, researchers at the University of California San Diego School of Medicine used a range of methods to identify and assess targeted metabolites in blood plasma from CFS patients. They found a specific chemical signature for CFS and underlying biology very similar to the state of hypometabolic conditions like caloric restriction, diapause (period of suspended development), and hibernation. The study “Metabolic features of chronic fatigue syndrome” is published in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS). CFS is often difficult and expensive to diagnose. Although individual tests may be affordable and possibly covered by medical insurance, many patients endure a diagnostic journey that results in substantial personal expenses, absence from the workplace, and significant reductions in quality of life. Health care professionals are also frustrated by the lack of an objective technology that can assist with diagnosis. Attempts at using analytes in blood, cerebrospinal flu
Subscribe or to access all post and page content.


  1. Kerry Kaminski says:

    Yet another psychological affliction has become a real disease. I hope that one day the word “biopsychosocial” will be dropped when talking about fibromyalgia as well.

  2. Curls says:

    I got sick when it was still questioned as psychological. One day I sat on the middle flight of steps in my house, waiting until I had energy to walk up the rest. Months before it’d be easy to climb.

    As I sat and thought about how it might be emotionally based, I thought – I’d be insane to think that. The emperor has no clothes on. For griminy sake, I’m sitting in the middle of my stairs, because I CAN NOT go up. There’s nothing emotionally about it. I’m not insane enough to think this set of data is “an emotional illness.”

    I got a plant for the middle stairs window sill so I’d have something to look at while I sat there many times each week.

Leave a Comment

Your email address will not be published. Required fields are marked *