Hyperactive Parathyroid May Trouble Women with Fibromyalgia, Study Reports

Hyperactive Parathyroid May Trouble Women with Fibromyalgia, Study Reports

Women with fibromyalgia have a high incidence of hyperparathyroidism, a disease caused by an overactive parathyroid, according to a study titled “High frequency of asymptomatic hyperparathyroidism in patients with fibromyalgia: random association or misdiagnosis?” and published in the journal Revista Brasileira de Reumatologia.

Fibromyalgia and hyperparathyroidism share a range of symptoms, including fatigue, arthralgia, myalgia, sleep disturbances, depression, anxiety and memory impairment, which increase the chances for an improper diagnosis. Primary hyperparathyroidism is a disease caused by a hyperactive parathyroid, which are small endocrine glands located in the neck, next to the thyroid, and responsible for the secretion of a hormone, the parathyroid, that regulates calcium levels in the body.

Researchers determined the frequency of asymptomatic hyperparathyroidism in a sample of patients with fibromyalgia by performing a cross-section study that enrolled 100 women with fibromyalgia and 57 healthy women, as controls. Additionally, they measured the levels of parathyroid hormone, calcium and albumin, correlating them with symptoms in the fibromyalgia group.

Fibromyalgia patients exhibited normal values of mean serum calcium and parathyroid hormone (9.6 ± 0.98 mg/dL and 57.06 ± 68.98 pg/mL, respectively). However, the levels of the parathyroid hormone were significantly higher when compared to the control group. Hypercalcemic (high calcium levels) hyperparathyroidism was detected in 6 percent of patients with fibromyalgia, but only 17 percent of these women had high levels of parathyroid hormone exhibiting normocalcemic (normal calcium levels) hyperparathyroidism. Researchers found no association between hyperparathyroidism and FM symptoms, with the only exception being epigastric pain.

These results show that in women with fibromyalgia a high frequency of hyperparathyroidism and of normocalcemic hyperparathyroidism exists compared to the general population. Researchers note, however, that these results are preliminary and additional studies with a larger number of patients are necessary to determine and confirm the association between the two diseases, fibromyalgia and hyperparathyroidism, and if high levels of parathyroid hormone are a characteristic of fibromyalgia pathophysiology.

Determining calcium and parathyroid hormone serum levels may be important for fibromyalgia patients. If alterations in these parameters are observed, researchers suggest patients should be screened for primary hyperparathyroidism.

2 comments

  1. anonymous says:

    Although this is not new news, thank you for sharing.

    The American Association of Endocrine Surgeons patient education website, with it’s accompanying experienced endocrine surgeon-locator is an excellent resource for unbiased information for both the patient and provider communities.

  2. Helen says:

    I have had a severe form of Fibromyalgia for thirty three years. I have had a Parathyroidectomy for an Adenoma (found after I was hospitalised with Kidney Stones) and a Hysterectomy for severe Endometriosis. I also have Chronic Migraine, Sleep Apnoea, IBS, Spondylitis, Severe Chemical sensitivity and nerve damage. All stemming from Fibromyalgia. A also have severe Arthritis – I think that this could also be caused by Fibromyalgia. I also have Liver Damage that I believe is caused by the medication that I have take over the years (by the way – I don’t drink alcohol or smoke!)
    BUT – I still find it very difficult to find a doctor who knows anything about the disease. Some doctors have never even heard of it. I have even been to a doctor who said that he thought that it wasn’t really a disease —- just something people used to get time off work! I explained to him – that as an Old Aged Pensioner – this certainly didn’t apply to me!
    As there are no “visible” symptoms —- people do not even believe that you are REALLY sick! If I had a broken leg I would get much more sympathy!!!
    I was once a Social Butterfly — but now I don’t socialise AT ALL. I prefer being alone, even shopping is now a chore. I keep busy with hobbies and the Internet at home – where I can have a rest if I am too fatigued (which is often!) — I just don’t like face to face contact as I never know if I will be up to interacting with people.
    The only relief I have had for the excruciating muscle pain and 24/7 Migraines that I endured for twenty five years was with Bowen Therapy and Ionic Foot De-toxing. You need both done for it to work.
    I now have my own Ionic Foot De-Tox machine, so I just have Bowen Therapy done and go home and do a de-tox. It is difficult getting the settings right — but so much worth it!! I have had an Ionic Foot De-tox in a shopping centre “Therapy” place when I was away from home – in a bid to relieve the pain – but it didn’t work. They didn’t even get the salinity level right (which I brought to their attention!)- and I think that their Anode was worn out. That was when I decided to buy my own De-Tox unit.
    Fibromyalgia is a horrible disease. I think my Fibromyalgia might be caused by (or exacerbated by) a crushed Brainstem, as I have severe damage to my Cervical Spine as well. This would explain the Sleep Apnoea component.
    I hope one day that the Medical Profession will find a cure for Fibromyalgia — maybe Genetic Manipulation as it certainly has a genetic component (I have other members of my family who also suffer with it) –but it is a very complicated disease and I don’t hold out much hope for the near future.
    All I can advise other Fibromyalgia sufferers to do is KEEP RESEARCHING!!!
    Cheers
    Helen

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