FM Seen to Further Aggravate Symptoms of Spondyloarthritis

FM Seen to Further Aggravate Symptoms of Spondyloarthritis
Coexistence of fibromyalgia (FM) in patients with spondyloarthritis (SpA) impacts patient-reported outcomes for disease activity and treatment responses, according to the study, “Evaluation of the impact of fibromyalgia in disease activity and treatment effect in spondyloarthritis,” published in the Arthritis Research & Therapy journal. FM often co-exists with SpA, a term that includes a spectrum of chronic inflammatory diseases involving both the joints and the entheses (the sites where the ligaments and tendons attach to the bones). As a result, this FM-SpA association presents diagnostic and treatment dilemmas, since some SpA symptoms (e.g., pain at entheses, fatigue, stiffness, and tenderness) can also be found in FM patients. The team of researchers estimated the prevalence of FM in a population of patients with SpA and compared the demographics/disease features, and the effects of TNF inhibitor (TNFi) treatment in patients with and without FM. To this end, the team recruited patients (18 and older) with a diagnosis of SpA according to a rheumatologist; FM diagnosis was defined by a score equal or superior to 5/6 in the Fibromyalgia Rapid Screening Tool (FiRST). In total, 196 SpA patients participated in the study with 42 patients (21.4 percent) positive for FM. Researchers found no statistical significant differences in the prevalence of FM when comparing the fulfillment of the Assessment of the Spondyloarthritis International Society (ASAS) criteria for peripheral/axial SpA. No differences were found for imaging versus the clinical arm of the ASAS criteria. Impor
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