Is SAM-e an Effective Treatment for Fibromyalgia?

Is SAM-e an Effective Treatment for Fibromyalgia?
SAM-e, a nonpharmaceutical supplement that has been championed anecdotally as effective in treating fibromyalgia and a wide range of other disorders, may not be the wonder drug that so many are seeking to help ease their pain. The National Institutes of Health (NiH) describes fibromyalgia syndrome as a common, chronic disorder characterized by widespread pain, diffuse tenderness, and a number of other symptoms. Often considered an arthritis-related condition, fibromyalgia is not truly a form of arthritis because it does not cause inflammation or damage to joints, muscles, or other body tissues. But like arthritis, fibromyalgia can cause significant pain and fatigue, and can interfere with a person’s ability to carry on daily activities. It is also considered a rheumatic disorder -- a medical condition that impairs the joints and or soft tissues and causes widespread chronic pain. Other symptoms include debilitating fatigue, sleep disturbance and joint stiffness. Currently, only three medications -- duloxetine (Cymbalta), milnacipran (Savella), and pregabalin (Lyrica) -- are approved by the U.S. Food and Drug Administration (FDA) for treating fibromyalgia. Duloxetine was originally developed as an antidepressant, but is used to treat other disorders, such as chronic migraines. Milnacipran is similar to another anti-depressant drug, but is FDA-approved only for fibromyalgia. Pregabalin was developed to treat chronic pain caused by damage to the nervous system. Some people with fibromyalgia report varying degrees of success with complementary and alternative therapies, including massage, movement therapies such as Pilates and the Feldenkrais method, chiropractic, acupuncture, light therapy, reflexology, and various herbs and dietary supplements. The r
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