Fibromyalgia Symptoms Relieved by Testosterone Gel, Study Shows

Fibromyalgia Symptoms Relieved by Testosterone Gel, Study Shows
Researchers have recently tested testosterone as an alternative treatment to alleviate symptoms in fibromyalgia patients, and report that an early study shows it to be effective in managing chronic pain with potentially fewer side effects than in existing treatments. The study entitled, Treatment of pain in fibromyalgia patients with testosterone gel: Pharmacokinetics and clinical response,” was published in the journal International Immunopharmacology. Current treatments for fibromyalgia (FM) including non-steroidal anti-inflammatory drug analgesics (NSAIDS), morphine-related opioid analgesics, and antidepressants, may cause gastrointestinal tract irritation, hyperplasia and sexual dysfunction. The mean age of FM onset in women, 44-53 years, overlaps with the mean age for menopause, 51 years, and several evidences have linked testosterone levels to pain, leading researchers to test whether testosterone therapy in these women could reduce pain without the side effects of common treatments. The team conducted a Phase I/II pilot trial in 12 patients to verify whether testosterone delivered daily in the form of a transdermal gel could significantly increase serum testosterone levels, and treat the chronic pain and fatigue symptoms of FM. They select women aged between 40–55 years who had been diagnosed with FM using the American College of Rheumatology (ACR) criteria. Study participants were not receiving hormone therapy and kept taking their medication, excep
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