No Lactic Acid Metabolic Differences in Patients With Fibromyalgia, Migraine

No Lactic Acid Metabolic Differences in Patients With Fibromyalgia, Migraine
Findings from a recent study published in the Revista Brasileira de Reumatologia (English Edition) revealed that patients with fibromyalgia, migraine or both do not exhibit any differences in the metabolism of lactic acid before, during or after aerobic or anaerobic exercise compared to healthy volunteers. Migraines are a chronic neurological disorder with genetic characteristics that modulate a dysfunction in brain electrical activity, and are characterized by recurrent episodes of headache that worsens with physical activity. Lactic acid usually increases during high-intensity physical activity and is related to a decline in muscle strength and pain generation during exercise. Additionally, the increase in lactic acid observed during exercise has been shown to trigger migraine attacks with aura. Fibromyalgia is a chronic pain condition of unknown etiology characterized by widespread spontaneous muscle pain and tenderness to palpation. The correlation between fibromyalgia and migraine varies from 22 to 50% of cases. However, the ratio of lactic acid production in patients with migraine and fibromyalgia, as well as the influence of this metabolite in the pathophysiology of these diseases, remains poorly understood. To address this unmet clinical issue, in the study entitled “
Subscribe or to access all post and page content.