Electroacupuncture Shown To Be Effective Pain Therapy in Fibromyalgia Mouse Model

Electroacupuncture Shown To Be Effective Pain Therapy in Fibromyalgia Mouse Model
Researchers at China Medical University and China Medical University Hospital in Taiwan recently published in the journal PLoS One new findings that electroacupuncture, through specific molecular pathways, can suppress pain in a fibromyalgia mouse model. The study is entitled “Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK.” Fibromyalgia is a medical disorder characterized by a set of symptoms that includes widespread chronic musculoskeletal pain, incapacitating fatigue, stiffness and numbness in certain parts of the body, painful response to pressure, headaches, unrefreshing sleep (poor sleep quality), anxiety or depression and mood alterations. Fibromyalgia can affect people’s ability to conduct simple daily tasks, compromising their quality of life. It is estimated that 5 to 15 million Americans are affected by the disorder, especially women. The causes of fibromyalgia are unclear, but it is thought that genetic, neurophysiological and psychosocial mechanisms are involved. The activation of acid-sensitive ion channels has been previously suggested to contribute to muscle pain in fibromyalgia patients. The protein pERK (phosphorylated extracellular signals regulated kinase) and members of the transient receptor potential vanilloid (TRPV) family of channels have been implicated in physiological pain and suggested to be altered in chronic pain conditions such
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