Could Fibromyalgia and Chronic Fatigue Syndrome be Caused by the Hepatitis B Vaccine?

Could Fibromyalgia and Chronic Fatigue Syndrome be Caused by the Hepatitis B Vaccine?

Researchers from Israel have found a possible link between some cases of chronic fatigue syndrome (CFS) and fibromyalgia (FM) and the hepatitis B vaccine. The study was published in Immunologic Research.

The purpose of this research was to gather information about people who had been diagnosed with FM or CFS after receiving the hepatitis B vaccination, spurred by patient reports of a possible association. The researchers used recently developed criteria for identifying autoimmune (auto-inflammatory) syndromes induced by adjuvants -- known by the acronym ASIA -- to try to find common clues that link FM, CFS and HBV vaccination. Led by Nancy Agmon-Levin and Yaron Zafrir of The Zabludowicz Center for Autoimmune Diseases, Tel-Hashomer, Israel, the researchers analyzed medical records from 19 patients, with an average age of 29 years, who acquired CFS and/or FM after receiving a hepatitis B vaccine. All of the study participants received the vaccine between 1990-2008 at different medical centers in the United States. The investigators collected data on medical history, number of vaccine doses, immediate and long term post-immunization side effects and clinical problems. They also studied any available blood tests, imaging results, treatments and outcomes of those treatments. The scientists found that 68% of the study participants were females and 21% had a background of autoimmune disease--either in their own medical history or in that of their family. The average time from the last dose of hepatitis B vaccine to the start of CFS or FM symptom
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